Searchable, peer-reviewed, open-access proceedings from bioscience and biomedical conferences

bp0012cpr17 | Programmes for Controlled Reproduction | CPR1985

Control of time of parturitionin pigs

Guthrie H. D. ,

Summary. Injection of prostaglandin (PG) F-2ct or its analogues has provided a . technique to induce parturition after Day 110 of gestation in the sow. The mean interval from PG injection to parturition ranges from 24 to 28 h, but only 50-60% of the sows farrow during an 8-10 h working day, and as many as 20% of sows may begin parturition before the injection of PG or > 22 h after the injection. The duration of parturition is positively associated with...

bp0016cpr2 | Development of The Follicleand Corpus Luteum | CPR2001

Apoptosis during folliculogenesis in pigs

Guthrie H. D. , Garrett W. M.

The number of female germ cells in pig fetuses decreases by 70% between day 50 after mating and day 300 after birth. Approximately 55% of antral follicles undergo degeneration (atresia) except during the 3 days before oestrus, when only 15% of the follicles survive to ovulate. Apoptosis, a form of programmed cell death, is recognized as the mechanism of germ cell death and follicle atresia at all stages of folliculogenesis. The internucleosomal cleavage of genomic DNA ca...

bp0014cpr8 | Ovarian and Uterine Function | CPR1993

The role of insulin-like growth factors and epidermal growth factor-related peptides in intraovarianregulation in the pig ovary

Hammond J. M. , Samaras S. E. , Grimes R. , Leighton J. , Barber J. , Canning S. F. , Guthrie H. D. ,

The autocrine and paracrine role of the insulin-like growth factors (IGFs) and epiderrnal growth factor (EGF)-related peptides in pig ovary are reviewed. For convenience, each of these regulatory systems is divided into several interactive components: regulated expression of the growth factors, growth factor reception at the cell surface and intracellular action of the growth factors. In addition, the concept of regulated bioavailability and targeting of growth factors in...